User:Mr. Ibrahem/Propantheline

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Mr. Ibrahem/Propantheline
Clinical data
Other namesPropantheline bromide
AHFS/Drugs.comMonograph
MedlinePlusa684020
Drug classAntimuscarinic[1]
Identifiers
  • N-isopropyl-N-methyl-N-{2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl}propan-2-aminium bromide
Chemical and physical data
FormulaC23H30NO3
Molar mass368.497 g·mol−1
3D model (JSmol)
  • [Br-].O=C(OCC[N+](C(C)C)(C(C)C)C)C2c3c(Oc1c2cccc1)cccc3
  • InChI=1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1 checkY
  • Key:XLBIBBZXLMYSFF-UHFFFAOYSA-M checkY
 ☒NcheckY (what is this?)  (verify)

Propantheline is a medication used to treat excessive sweating, irritable bowel syndrome, and loss of bladder control.[2] It has been used for peptic ulcer disease; however evidence to support this use is poor.[1] It is taken by mouth.[1]

Common side effects include dry mouth and blurry vision.[1] Other side effects may include arrhythmias, anaphylaxis, and sleepiness.[2][1] Safety in pregnancy is unclear.[1] It is an antimuscarinic.[1]

Propantheline was approved for medical use in the United States in 1953.[1] In the United Kingdom 112 tablets of 15 mg costs the NHS about £20 in 2021.[2] In the United States this amount costs about 300 USD.[3]

References[edit]

  1. ^ a b c d e f g h i "Propantheline Monograph for Professionals". Drugs.com. Archived from the original on 26 January 2021. Retrieved 29 October 2021.
  2. ^ a b c d e BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 94. ISBN 978-0857114105.
  3. ^ "Propantheline Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 26 January 2021. Retrieved 29 October 2021.