User:Mr. Ibrahem/Pindolol

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Mr. Ibrahem/Pindolol
Skeletal formula of pindolol
Space-filling model of the pindolol molecule
Clinical data
Trade namesVisken, others[1]
AHFS/Drugs.comMonograph
MedlinePlusa684032
Pregnancy
category
  • AU: C
Routes of
administration		By mouth, intravenous
Drug classNonselective beta blocker[2]
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability50% to 95%
MetabolismLiver
Elimination half-life3–4 hours
ExcretionKidney
Identifiers
  • (RS)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol
Chemical and physical data
FormulaC14H20N2O2
Molar mass248.326 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • CC(C)NCC(O)COc2cccc1[nH]ccc12
  • InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3 ☒N
  • Key:JZQKKSLKJUAGIC-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Pindolol, sold under the brand name Visken among others, is a medication used to treat high blood pressure and angina.[3][4] It is a less preferred treatment for high blood pressure.[2] It is taken by mouth.[3] Maximum blood pressure effects may take two weeks.[2]

Common side effects include trouble sleeping, dizziness, tiredness, swelling, joint pain, and itchiness.[2] Other side effects may include anaphylaxis, bronchospasm, and heart failure.[2] Use in pregnancy may cause a slow heart rate in the baby.[5] It is a nonselective beta blocker.[2]

Pindolol was approved for medical use in the United States in 1982.[2] It is available as a generic medication.[4] In the United Kingdom 100 tablets of 5 mg costs the NHS about £8 as of 2021.[4] This amount in the United States costs about 40 USD.[6]

References[edit]

  1. ^ Drugs.com International brand names for pindolol Archived 2017-10-01 at the Wayback Machine Page accessed Sept 4, 2015
  2. ^ a b c d e f g h "Pindolol Monograph for Professionals". Drugs.com. Archived from the original on 7 August 2021. Retrieved 28 October 2021.
  3. ^ a b c "DailyMed - PINDOLOL tablet". dailymed.nlm.nih.gov. Archived from the original on 28 October 2021. Retrieved 28 October 2021.
  4. ^ a b c d e BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 164. ISBN 978-0857114105.
  5. ^ "Pindolol (Visken) Use During Pregnancy". Drugs.com. Archived from the original on 7 August 2021. Retrieved 28 October 2021.
  6. ^ "Pindolol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 28 October 2021.
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