User:Mr. Ibrahem/Phenelzine
 | |
 | |
| Clinical data | |
|---|---|
| Trade names | Nardil |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682089 |
| License data |
|
| Pregnancy category |
|
| Routes of administration | By mouth |
| Drug class | Monoamine oxidase inhibitor (MAOI)[2] |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Metabolism | Liver |
| Onset of action | Up to 4 wks[3] |
| Elimination half-life | 11.6 hours |
| Excretion | Urine |
| Identifiers | |
| |
| Chemical and physical data | |
| Formula | C8H12N2 |
| Molar mass | 136.198 g·mol−1 |
| 3D model (JSmol) | |
| Boiling point | 74 °C (165 °F) |
| |
| |
| (verify) | |
Phenelzine, sold under the brand name Nardil among others, is a medication used to treat depression and bulimia.[2] It is taken by mouth.[2] Benefits can take up to 4 weeks to occur.[3]
Common side effects include dizziness, headache, trouble sleeping, twitching, dry mouth, weight gain, and sexual dysfunction.[2] Other side effects may include suicide, bipolar, and high blood pressure.[2] Use is not recommended in people with kidney or liver problems.[2] It is a monoamine oxidase inhibitor (MAOI) made from hydrazine.[2]
Phenelzine was approved for medical use in the United States in 1961.[2] In the United States 60 tablets of 15 mg costs about 45 USD as of 2021.[4] In the United Kingdom it is only available by special order.[3]
References[edit]
- ^ a b "Phenelzine (Nardil) Use During Pregnancy". Drugs.com. 3 March 2020. Archived from the original on 12 July 2020. Retrieved 11 July 2020.
- ^ a b c d e f g h i j "Phenelzine Monograph for Professionals". Drugs.com. Archived from the original on 23 January 2021. Retrieved 27 October 2021.
- ^ a b c d BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 382. ISBN 978-0857114105.
- ^ "Phenelzine Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 3 August 2020. Retrieved 28 October 2021.