User:Mr. Ibrahem/Naphazoline

Mr. Ibrahem/Naphazoline
Clinical data
Trade names	Naphcon-a, Clear Eyes Red Relief, Visine A, others
AHFS/Drugs.com	Monograph
Routes of; administration	Nasal spray, eye drops
Drug class	Alpha adrenergic agonist
Legal status
Legal status	In general: Over-the-counter (OTC);
Identifiers
	IUPAC name 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole;
Chemical and physical data
Formula	C14H14N2
Molar mass	210.274 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES N\1=C(\NCC/1)Cc2cccc3c2cccc3;
	InChI InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16) ; Key:CNIIGCLFLJGOGP-UHFFFAOYSA-N ;
	(what is this?) (verify)

Naphazoline, sold under many brand names, is a medication used to treat a stuffy nose or eye redness due to minor irritation.^[1] It is available as a nasal spray or eye drops.^[1]

Common side effects include blurry vision and stinging.^[1] Other side effects may include recurrence of stuffiness following stopping use, headache, palpitations, and nervousness.^[1] Safety in pregnancy is unclear.^[1] It works by activating alpha adrenergic receptor which cases small arteries to narrow.^[1]

Naphazoline was patented in 1934 and came into medical use in 1942.^[2] It is available as a generic medication and over the counter.^[1] In the United States 15 ml of solution costs about 14 USD.^[3]

References[edit]

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Naphazoline Monograph for Professionals". Drugs.com. Archived from the original on 23 January 2021. Retrieved 11 November 2021.
^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 552. ISBN 9783527607495. Archived from the original on 2016-12-29. Retrieved 2020-10-19.
^ "Naphazoline ophthalmic Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 11 November 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Naphazoline Monograph for Professionals". Drugs.com. Archived from the original on 23 January 2021. Retrieved 11 November 2021.

[Fis2006-2] Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 552. ISBN 9783527607495. Archived from the original on 2016-12-29. Retrieved 2020-10-19.

[3] "Naphazoline ophthalmic Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 11 November 2021.

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