User:Mr. Ibrahem/Aminocaproic acid

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Mr. Ibrahem/Aminocaproic acid
Skeletal formula
Ball-and-stick model of the zwitterionic form of the molecule found in the crystal structure[1][2]
Clinical data
Trade namesAmicar
Other namesε-aminocaproic acid, ε-Ahx
AHFS/Drugs.comMonograph
MedlinePlusa608023
License data
Routes of
administration		By mouth, intravenous
Legal status
Legal status
Pharmacokinetic data
MetabolismKidney
Elimination half-life2 hours
Identifiers
  • 6-aminohexanoic acid
Chemical and physical data
FormulaC6H13NO2
Molar mass131.175 g·mol−1
3D model (JSmol)
Melting point205 °C (401 °F)
  • C(CCC(=O)O)CCN
  • InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9) checkY
  • Key:SLXKOJJOQWFEFD-UHFFFAOYSA-N checkY
  (verify)

Aminocaproic acid, sold under the brand name Amicar among others, is a medication used to treat certain bleeding disorders.[3] This may include bleeding due to fibrinolysis such as may occur following heart surgery, abruptio placentae, liver cirrhosis, and in cancer; bleeding within the eye; and hereditary hemorrhagic telangiectasia.[3][4] It may be taken by mouth or injection into a vein.[4]

Common side effects include nausea, abdominal pain, diarrhea, dizziness, fever, shortness of breath, headache, swelling, and itchiness.[4] Other side effects may include muscle breakdown.[4] It should generally not be used in people with bleeding from within the kidney.[4] Safety in pregnancy is unclear.[4] It is a form of carboxylic acid that decreases fibrinolysis.[4]

Aminocaproic acid was approved for medical use in the United States in 1964.[4] It is available as a generic medication.[6] In the United States 15 pills of 500 mg costs about 44 USD as of 2022.[6]

References[edit]

  1. ^ G. J. Reiss (2010). "CSD Communication AMCAPR11: 6-Aminohexanoic acid". Cambridge Structural Database: Access Structures. Cambridge Crystallographic Data Centre. doi:10.5517/ccv38nv. Archived from the original on 2021-11-04. Retrieved 2021-08-18.
  2. ^ Bodor, Géza; Bednowitz, Allan L.; Post, Ben (1967). "The crystal structure of ε-aminocaproic acid". Acta Crystallographica. 23 (3): 482–490. doi:10.1107/S0365110X67003019.
  3. ^ a b c d "Amicar- aminocaproic acid solution Amicar- aminocaproic acid tablet". DailyMed. 9 October 2020. Archived from the original on 13 November 2020. Retrieved 11 November 2020.
  4. ^ a b c d e f g h i "Aminocaproic Acid Monograph for Professionals". Drugs.com. Archived from the original on 12 November 2020. Retrieved 14 January 2022.
  5. ^ "Aminocaproic acid (Amicar) Use During Pregnancy". Drugs.com. 29 April 2020. Archived from the original on 29 November 2020. Retrieved 11 November 2020.
  6. ^ a b "Aminocaproic Acid Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 13 October 2016. Retrieved 14 January 2022.
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