User:Mr. Ibrahem/Almotriptan
Clinical data | |
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Trade names | Axert |
Other names | Almotriptan hydrogen malate[1] |
AHFS/Drugs.com | Monograph |
MedlinePlus | a603028 |
License data |
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Routes of administration | By mouth |
Drug class | Triptan[1] |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Bioavailability | 70% |
Protein binding | 35% |
Metabolism | Liver |
Elimination half-life | 3–4 hours |
Identifiers | |
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Chemical and physical data | |
Formula | C17H25N3O2S |
Molar mass | 335.47 g·mol−1 |
3D model (JSmol) | |
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Almotriptan, sold under the brand name Axert among others, is a medication used to treat migraine headaches.[1] It may be used in people over the age of 11.[6] There is a lack of evidence for cluster headaches.[6] It is taken by mouth.[1]
Common side effects include nausea, dry mouth, sleepiness, and numbness.[5] Other side effects may include heart problems, stroke, Raynaud syndrome, serotonin syndrome, and medication overuse headaches.[5] Use in pregnancy may harm the baby.[5] It is a triptan.[1]
Almotriptan was patented in 1992 and approved for medical use in 2000.[7] It is available as a generic medication.[1] In the United Kingdom it costs the NHS about £2.80 a dose as of 2021.[1] This amount in the United States is about 9 USD.[8]
References[edit]
- ^ a b c d e f g h i BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 500. ISBN 978-0857114105.
- ^ "Almotriptan tablet, film coated". DailyMed. Archived from the original on 24 March 2021. Retrieved 17 February 2021.
- ^ "Axert- almotriptan malate tablet, coated". DailyMed. Archived from the original on 23 March 2021. Retrieved 17 February 2021.
- ^ "Archive copy" (PDF). Archived (PDF) from the original on 2021-11-05. Retrieved 2021-02-18.
{{cite web}}
: CS1 maint: archived copy as title (link) - ^ a b c d "DailyMed - ALMOTRIPTAN MALATE- almotriptan tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 22 March 2021. Retrieved 14 January 2022.
- ^ a b "Almotriptan Monograph for Professionals". Drugs.com. Archived from the original on 23 January 2021. Retrieved 14 January 2022.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 531. ISBN 9783527607495. Archived from the original on 2020-10-23. Retrieved 2021-02-18.
- ^ "Almotriptan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 14 June 2016. Retrieved 14 January 2022.