Talk:Isozyme

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Untitled[edit]

I have a question concerning the term isozym. I would like to compare two enzymes which use the same substrate and produce the identical product. The two enzymes however use different cofactors. In one case the "cofactor" is molecular Oxygen and NADP+ and in the other case the enzyme uses H2O and electrons are transferred somehow into the membrane of the bacterium. Is it feasible to talk of isozymes ? Answer Yah why not, since they use the same substrate and produce the same product/function.It does make sense because mutation or insertion deletion might have occured resulting the enzymes to have different binding cofactor sites of which still generating the formation of the same product or function (transportation of the electron).152.106.240.139 10:32, 12 August 2006 (UTC) 152.106.240.139 10:32, 12 August 2006 (UTC) Sandiso Peter(UJHB)[reply]

When typing in the search word Allozyme, I was directed to this page leading me to believe that an Isozyme was equivalent to an Allozyme. Upon presenting this to my chemistry professor, I was told that allozymes and isozymes were not equivalent and that it was a very common mistake to refer to them as such. I believe more emphasis should be placed on this within the article as they are distinctly different from each other and although these articles had been merged in the past, they should not have been.

I've fixed the redirect now. There's a tiny bit of informtion there but it needs a lot of work. This isn't my particular area so I won't really be able to help a great deal but it's a start. Medos ^{(talk • contribs)} 12:23, 27 February 2008 (UTC)[reply]

I've added this to the allozyme talk page, may help here too? I believe this is the first mention of the term allozyme: "We propose the term allozyme for the variant proteins produced by allelic forms of the same locus, to avoid the now common confusion with isozymes which are the various polymers produced from monomers specified by different loci." from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1212247/pdf/841.pdf Prakash, Satya, R. C. Lewontin, and J. Lo Hubby. "A molecular approach to the study of genic heterozygosity in natural populations IV. Patterns of genic variation in central, marginal and isolated populations of Drosophila pseudoobscura." Genetics 61, no. 4 (1969): 841.

91.67.141.25 (talk) 14:32, 16 December 2014 (UTC) The open paragraph should be changed - since the first 3 sentences are plagiarized from Stryer's Biochemistry. 4.225.238.61 (talk) 00:17, 13 April 2008 (UTC)[reply]

This is most definitely NOT a B-class article. It has misinformation, and is missing substantial amounts of other important information. For example, the use of isoenzyme (the correct term, by the way) techniques in medical diagnosis, in gene mapping, in species identification, in cell culture contamination detection are a few of the missing areas. Chemistmax (talk) 14:12, 10 October 2008 (UTC)[reply]

The entire article doesnt have any citation just reference section has some books listed, it would be very kind if someone can provide citation to the article. there is no citation in the article. Demi lion (talk) 12:55, 13 June 2014 (UTC)[reply]

I'm pretty sure the definition of "isozyme" is not from the Hunter/Markert 1957 paper in Science, since no sentence cited appears in the paper in question (but it is an example of a discovered isozyme). I believe the term "isozyme" was defined later by Markert and Moller in 1959, see this paper, last sentence of the first paragraph: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC222630/pdf/pnas00192-0095.pdf 91.67.141.25 (talk) 13:49, 16 December 2014 (UTC)[reply]

Assessment comment[edit]

The comment(s) below were originally left at Talk:Isozyme/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

This is most definitely NOT a B-class article. It has misinformation, and is missing substantial amounts of other important information. For example, the use of isoenzyme (the correct term, by the way) techniques in medical diagnosis, in gene mapping, in species identification, in cell culture contamination detection are a few of the missing areas. Chemistmax (talk) 14:06, 10 October 2008 (UTC)[reply]

Last edited at 14:06, 10 October 2008 (UTC). Substituted at 19:11, 29 April 2016 (UTC)