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Subrahmanyan Chandrasekhar, FRS (/ˌʌndrəˈʃkɑːr/ ; Tamil: சுப்பிரமணியன் சந்திரசேகர்; October 19, 1910 – August 21, 1995) was an Indian-American astrophysicist who, with William A. Fowler, won the 1983 Nobel Prize for Physics for key discoveries that led to the currently accepted theory on the later evolutionary stages of massive stars. Chandrasekhar was the nephew of Sir Chandrasekhara Venkata Raman, who won the Nobel Prize for Physics in 1930.

Chandrasekhar's most notable work was the astrophysical Chandrasekhar limit. The limit describes the maximum mass of a white dwarf star, ~ 1.44 solar mass, or equivalently, the minimum mass above which a star will ultimately collapse into a neutron star or black hole (following a supernova). The limit was first calculated by Chandrasekhar in 1930 during his maiden voyage from India to Cambridge, England, for his graduate studies. In 1999, the NASA named the third of its four "Great Observatories" after Chandrasekhar. The Chandra X-ray Observatory was launched and deployed by Space Shuttle Columbia on July 23, 1999. The Chandrasekhar number, an important dimensionless number of magnetohydrodynamics, is named after him. The asteroid 1958 Chandra is also named after Chandrasekhar. American astronomer Carl Sagan, who studied Mathematics under Chandrasekhar, at the University of Chicago, praised him in the book The Demon-Haunted World: "I discovered what true mathematical elegance is from Subrahmanyan Chandrasekhar." From 1952 to 1971 Chandrasekhar also served as the editor of the Astrophysical Journal.

He was awarded the Nobel Prize in Physics in 1983 for his studies on the physical processes important to the structure and evolution of stars. Chandrasekhar accepted this honor, but was upset that the citation mentioned only his earliest work, seeing it as a denigration of a lifetime's achievement. He shared it with William A. Fowler.