KCNQ1DN

KCNQ1 downstream neighbour
KCNQ1 downstream neighbour
	Predicted secondary structure and sequence conservation of KCNQ1DN
Identifiers
Symbol	KCNQ1DN
Rfam	RF01961
Other data
RNA type	Gene;
Domain(s)	Eukaryota;
SO	SO:0001463
PDB structures	PDBe

KCNQ1DN
Identifiers
Aliases	KCNQ1DN, BWRT, HSA404617, KCNQ1 downstream neighbor (non-protein coding), KCNQ1 downstream neighbor
External IDs	OMIM: 610980 GeneCards: KCNQ1DN
Gene location (Human)
Chr.	Chromosome 11 (human)
End	2,872,105 bp
RNA expression pattern
	Top expressed in
	substantia nigra; ; ganglionic eminence; ; hippocampus proper; ; prefrontal cortex; ; lymph node; ; putamen; ; hypothalamus; ; skeletal muscle tissue; ; muscle of leg; ; renal cortex;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	cellular component;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
	55539
	n/a
	ENSG00000237941; ENSG00000278855
	n/a
	Q9H478
	n/a
	NM_018722
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

KCNQ1 downstream neighbour (KCNQ1DN) is a long non-coding RNA gene. In humans, it is located on chromosome 11p15.5 between the CDKN1C and KCNQ1 genes. It is an imprinted gene, expressed from the maternal allele. Reduced expression of KCNQ1DN is observed in Wilms' tumours.^[3]

References[edit]

^ ^a ^b ^c ENSG00000278855 GRCh38: Ensembl release 89: ENSG00000237941, ENSG00000278855 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Xin Z, Soejima H, Higashimoto K, et al. (November 2000). "A novel imprinted gene, KCNQ1DN, within the WT2 critical region of human chromosome 11p15.5 and its reduced expression in Wilms' tumors". J. Biochem. 128 (5): 847–853. doi:10.1093/oxfordjournals.jbchem.a022823. PMID 11056398.