File:Schematic of the glypican-3 protein..tif
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Summary
| Description |
English: The human glypican-3 (GPC3) gene encodes a 70 kDa precursor protein of 580 amino acids. Upon translocation into the endoplasmic reticulum, the N-terminal signal peptide (SS; residues 1–24) and the C-terminal glycosyl-phosphatidylinositol (GPI) anchor addition signal (a predicted cleavage site: S560) are removed and the latter is replaced with a GPI anchor. The GPC3 precursor is cleaved into two subunits, NH2 terminus (residues Q25 – R358) and the GPI-anchored membrane-bound COOH terminus starting from S359. The three N-linked glycans (black lollipops; N124, N241 and N418) are indicated. |
| Date | |
| Source | Own work |
| Author | Bioshore |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 23:04, 31 May 2020 |  | 893 × 552 (1.43 MB) | Bioshore | Cross-wiki upload from en.wikipedia.org |
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