File:How random DNA libraries sample sequence space.pdf
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Summary
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English: Depiction of how DNA libraries created by random diversity-generation techniques sample the sequence space. The amino acid substituted into a given position is shown. Each dot or set of connected dots is one member of the library. Error-prone PCR randomly mutates some residues to other amino acids. Alanine scanning replaces each reside of the protein with alanine, one-by-one. Site saturation substitutes each of the 20 possible amino acids (or some subset of them) at a single position, one-by-one. |
| Date | |
| Source | Own work |
| Author | Rob Hurt |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:31, 4 April 2020 |  | 600 × 600 (22 KB) | Rob Hurt | Uploaded own work with UploadWizard |
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