ALG10B

ALG10B
Identifiers
Aliases	ALG10B, ALG10, KCR1, alpha-1,2-glucosyltransferase, ALG10 alpha-1,2-glucosyltransferase B
External IDs	OMIM: 603313 MGI: 2146159 HomoloGene: 107128 GeneCards: ALG10B
Gene location (Human)
Chr.	Chromosome 12 (human)
End	38,329,721 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	90,117,674 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; retinal pigment epithelium; ; tibia; ; germinal epithelium; ; ganglionic eminence; ; endometrium; ; islet of Langerhans; ; placenta; ; bronchial epithelial cell; ; thymus;
	Top expressed in
	hand; ; secondary oocyte; ; superior cervical ganglion; ; atrioventricular valve; ; otolith organ; ; trigeminal ganglion; ; utricle; ; endocardial cushion; ; medial ganglionic eminence; ; abdominal wall;
	More reference expression data
	n/a
Gene ontology
Molecular function	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity; glycosyltransferase activity; transferase activity; dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity;
Cellular component	integral component of membrane; plasma membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum;
Biological process	dolichol-linked oligosaccharide biosynthetic process; protein glycosylation; positive regulation of protein glycosylation; positive regulation of inward rectifier potassium channel activity;
	Sources:Amigo / QuickGO
Orthologs
	144245
	380959
	ENSG00000175548
	ENSMUSG00000075470
	Q5I7T1
	Q3UGP8
	NM_001013620; NM_001308340
	NM_001033441
	NP_001013642; NP_001295269
	NP_001028613
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-1,2-glucosyltransferase ALG10-B is an enzyme that in humans is encoded by the ALG10B gene.^[5] It is a member of the Dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase class of enzymes. It has ubiquitous expression in 27 tissues.^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175548 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000075470 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ UniProt ID: Q5I7T1. Retrieved 30 November 2019
^ "Entrez Gene: ALG10B ALG10 alpha-1,2-glucosyltransferase B". Retrieved 30 November 2019.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175548 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000075470 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] UniProt ID: Q5I7T1. Retrieved 30 November 2019

[entrez-6] "Entrez Gene: ALG10B ALG10 alpha-1,2-glucosyltransferase B". Retrieved 30 November 2019.

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