User talk:KimonoKagaku/sandbox

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Launching talk page. Ndeporzio (talk) 15:54, 6 April 2015 (UTC)[reply]

ndeporzio_KimonoKagaku_U3PR[edit]

I was unable to locate the original article that the user is editing. I have looked through both the english Wikipedia and simple english Wikipedia and could not find it. I am trying to retrace the histories of all "Alzheimer's Disease" articles to identify what contributions were made by this author. Ndeporzio (talk) 16:03, 6 April 2015 (UTC)[reply]

I need to note that reviewing this author's contributions has been very difficult because of the nature of the chosen article. The article is on "Alzheimer's Disease" on English Wikipedia but the article is actively and frequently edited. I will review the author's contribution from the time that they moved the article to their sandbox.

Summary[edit]

The author first makes a few additional comments about the relationship between slow-wave sleep (SWS) and next-day recall in Alzheimer's patients. They explain that more SWS correlated to an improved next-day recall ability in patients. Comments are made that Alzheimer's patients may have a constantly high Amyloid during the night which could result in heightened restlessness. However, the author points out that this could also be a result of the deregulation of Hypocretin, MCH, and melatonin in Alzheimer's patients. The author continues to discuss the promising treatment of patients via melatonin supplementation to improve sleep conditions. The author then makes a few comments on the data visualization of fMRI. The author then discusses the use of PSG, EEG, EOG, and EMG as diagnostic tools for studying patients. The author concludes by discussing further how the degradation of sleep conditions in the elderly correlates to the similar degradation of memory. The author explains the REM sleep is one means of judging sleep quality and that certain treatments like Donepezil have been used to improve REM sleep in its users. The author then again discusses the relation between SWS and next-day memory recall.

Major Points[edit]

My greatest concern with this article is that the current page for it is actively and frequently growing and changing while this article is being edited in the sandbox. Thus, many of the sections originally edited by the author have been since edited over on the actual page. Thus, integration of this page upon completion may prove difficult. With regards to the writing of the author my concerns were in particular with the diagnostic tools section as well as with the last section edited by the author. I believe the behavioral measures sections should be discussed with greater focus in the context of alzheimers - the section currently seems like it could be taken out of the article and serve as standalone pages on PSG, EEG, EOG, EMG, etc. In the last section, I believe much information on SWS and next-day memory recall may have been repeated from earlier edits made by the author in the sleep disruption section. Perhaps consider consolidating these two sections or alternatively to further distinguish the two in order to ensure information is being added in the latter section.

Minor Points[edit]

I believe the author did a great job adding quality citations to this article. Additionally, I believe the author identified those sections which other users requested more information on and fulfilled those requests by adding information. Yet, this article is latent with medical terms which are not exhaustively linked to their respective pages - spindles, for instance. I would suggest further linking throughout the article. Additionally, in reviewing the references section, there are multiple empty citations that should be filled. I would also suggest the author consider expanding the article through the development of new sections. Consider such sections as: the history of alzheimers, political/medical debate surround alzheimers, symptoms, treatments, etc. Ndeporzio (talk) 16:39, 6 April 2015 (UTC)[reply]