User talk:Fuse809/Archive 1

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Changes without an edit summary

In addition to the animated GIF I reverted, you made a series of changes to Aripiprazole without filling in the edit summary. Some of those changes may be self-explanatory, but even then, other editors can't see the changes themselves on the page history, so it's a good idea to put in a summary even then. The Crab Who Played With The Sea (talk) 09:10, 22 July 2013 (UTC)

A barnstar for you!

The Original Barnstar
For your contributions to Pharmocology items, by adding structural data Sfan00 IMG (talk) 20:32, 9 August 2013 (UTC)

References

Per WP:MEDRS we generally only use secondary sources like review articles and textbooks rather than primary sources. Thks Doc James (talk · contribs · email) (if I write on your page reply on mine) 14:39, 9 September 2013 (UTC)

You have had material you added removed by others for this reason aswell. I used primary sources when I first began and was corrected and adapted to this communities norm [1] Doc James (talk · contribs · email) (if I write on your page reply on mine) 00:40, 11 September 2013 (UTC)

MOS

Per the manual of style we only capatalize the first word in the lead.

Also we try to write in prose rather than lists. Not sure how to do this with side effects? Doc James (talk · contribs · email) (if I write on your page reply on mine) 01:57, 19 September 2013 (UTC)

Would also be good to write in simple language. So instead of xerostomia we can have dry mouth. Doc James (talk · contribs · email) (if I write on your page reply on mine) 09:58, 19 September 2013 (UTC)

Refs over one line

A minor point. If you put refs over one line it is easy to review changes that are made. Best Doc James (talk · contribs · email) (if I write on your page reply on mine) 21:42, 6 October 2013 (UTC)

It is easier to notices changes to the text when the ref is NOT spread out over a number of lines. See these edits as an example [2] as opposed to these [3] Doc James (talk · contribs · email) (if I write on your page reply on mine) 22:05, 6 October 2013 (UTC)

Caps

In the section headings typically only the first word is capitalized as per our WP:MOS. Best Doc James (talk · contribs · email) (if I write on your page reply on mine) 06:38, 11 October 2013 (UTC)

This is not a very good ref "Truven Health Analytics, Inc. DrugPoint® System (Internet) [cited 2013 Sep 18]. Greenwood Village, CO: Thomsen Healthcare; 2013." There is no link to the page / article in question. It appears closed. No indication that it is peer reviewed. We view sources like UpToDate the same. They can change and there is no record on how it was before. Doc James (talk · contribs · email) (if I write on your page reply on mine) 06:48, 11 October 2013 (UTC)
For medical content we typically use secondary sources per WP:MEDRS. Not sure why the adding of more primary sources in this edit? [4] Doc James (talk · contribs · email) (if I write on your page reply on mine) 06:58, 11 October 2013 (UTC)

DrugPoint is an accurate medical source, my university and the local hospital in my city uses it for much of its drug information. It may not be accessible to all but neither are many medical books so I don't see how this is a problem. UpToDate is peer-reviewed. Fuse809 (talk) 10:59, 11 October 2013 (UTC)

They are not static published sources. Neither of them are preferred sources. Feel free to ask others opinions at WT:MED. Better to use review articles. Doc James (talk · contribs · email) (if I write on your page reply on mine) 00:44, 12 October 2013 (UTC)

Significant changes in meaning and values to Tricyclic antidepressant

Hi. In this series of edits you made significant changes to the above article citing only on source: http://pdsp.med.unc.edu/pdsp.php

Can you please tell me what that source is and why it is reliable? Also, can you point me to where you found at least some of the categories and binding profile values that you updated? --Anthonyhcole (talk · contribs · email) 08:25, 4 December 2013 (UTC)

It is a database created by the National Institute of Mental Health and it contains a heap of Ki values and the reason why it is so reliable is because it has a large number of Ki values for each drug and the average of these values is what I used in these tables so instead of using say one journal article per piece of data (i.e. Ki value) I was using a composite of the data in a whole variety of journal articles. The categories you're mentioning is something I'm going to have to ask you to clarify as for the binding profile values I think I just answered that -- the PDSP database. I was following the algorithm for determining Ki values as was used for the Ki values in the antipsychotic chapter of Goodman and Gilman and hence I know I am using a scientifically accepted method for estimating Ki values. Fuse809 (talk) 08:44, 4 December 2013 (UTC)

This is out of my depth, so I've asked at WikiProject Molecular and Cellular Biology for someone to review your work. --Anthonyhcole (talk · contribs · email) 11:36, 4 December 2013 (UTC)
I think it is only valid to average Ki values is they are replicate measurements in the same assay from the same laboratory. In this case, it would also be appropriate to report the standard error of the mean (SEM). If these Ki values were obtained from different labs where the assay conditions may vary, then I think it would be more appropriate to report the range of values (min, max, median). Boghog (talk) 12:05, 4 December 2013 (UTC)

Doing that just crowds the tables, making them more difficult to read and can really confuse the average person. At least if we have one value and we tell them that the smaller the value the stronger the binding then they may be able to follow but if we give them ranges and SEMs we might as well through them into the deep end. I was following the method used by the authors of Goodman and Gilman and I think if it's good enough for them it's good enough for us. Fuse809 (talk) 12:26, 4 December 2013 (UTC)

OK, but at a minimum, it would be appropriate to include a footnote for each averaged table entry specifying that this value represents an average of two or more independent measurements. If a particular value is not an average, then this value should not be footnoted. Boghog (talk) 13:26, 4 December 2013 (UTC)

Please upload your chemical structures, etc. to Commons — as you have done in several cases before. --Leyo 08:30, 22 November 2013 (UTC)

Why don't you do so? It just causes work for other users. --Leyo 20:36, 4 December 2013 (UTC)

Usually because it makes more work for me when I'm at the upload form. Fuse809 (talk) 23:38, 4 December 2013 (UTC)

Have you ever used the prefilled form found at commons:Commons:Upload/Chemistry? It may even save time for you (and surely for others). --Leyo 09:34, 5 December 2013 (UTC)

Bolding

Why are some of the adverse effects bolded here [5]? Doc James (talk · contribs · email) (if I write on your page reply on mine) 06:08, 7 December 2013 (UTC)

Read my note and you'll know why. Fuse809 (talk) 08:32, 7 December 2013 (UTC)

Emedicine / medscape

These are passable sources sometimes but not really the best sources. Review articles or major textbooks are typically better. Best Doc James (talk · contribs · email) (if I write on your page reply on mine) 07:53, 17 April 2014 (UTC)

Also your MSR ref does not work. Doc James (talk · contribs · email) (if I write on your page reply on mine) 07:55, 17 April 2014 (UTC)

How doesn't it work? Secondly, I usually only use this ref when there's no better ref I can find. I know, I would much rather have something written than nothing. Fuse809 (talk) 08:09, 17 April 2014 (UTC)

Structure of heroin

Hi, I see that in this edit, you have replaced the molecular structure of heroin with an image you uploaded[6]. I don't know much about this but as discussed in this Help Desk question, it seems that your structure is missing the methyl part of the acetyl ester group, and instead have an -OH. Could you please check it. Thanks.···Vanischenu (mc/talk) 16:16, 17 April 2014 (UTC)

Oh so, so sorry and thank you for bringing this to my attention! I have fixed it! Fuse809 (talk) 16:40, 17 April 2014 (UTC)
Thank you! Regards···Vanischenu (mc/talk) 18:56, 17 April 2014 (UTC)

Apologies

Just saw the one line in the lead being removed. Missed the rest of your changes. Sorry for the revert and apologies. Doc James (talk · contribs · email) (if I write on your page reply on mine) 17:00, 21 April 2014 (UTC)

Apology accepted; thank you for taking the time and guts to apologise, I know I probably wouldn't have bothered. Fuse809 (talk) 17:04, 21 April 2014 (UTC)

Invitation join the new Physiology Wikiproject!

Physiology gives us an understanding of how and why things in the field of medicine happen. Together, let us jumpstart the project and get it going. Our energy is all it needs.

Based on the long felt gap for categorization and improvization of WP:MED articles relating to the field of physiology, the new WikiProject Physiology has been created. WikiProject Physiology is still in its infancy and needs your help. On behalf of a group of editors striving to improve the quality of physiology articles here on Wikipedia, I would like to invite you to come on board and participate in the betterment of physiology related articles. Help us to jumpstart this WikiProject.

  • Feel free to leave us a message at any time on the WikiProkect Physiology talk page. If you are interested in joining the project yourself, there is a participant list where you can sign up. Please leave a message on the talk page if you have any problems, suggestions, would like review of an article, need suggestions for articles to edit, or would like some collaboration when editing!
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Hoping for your cooperation! DiptanshuTalk 12:24, 27 April 2014 (UTC)

August 2013

Stop icon This is your last warning. The next time you disrupt Wikipedia, you may be blocked from editing without further notice. Many users have complained about your continued insertions of unusually-drawn 2D diagrams and animated 3D structures, but you have not bothered to respond. Wikipedia is a collaborative effort, where WP:CONSENSUS rules. If you decide not to participate in discussions about your edits and continue making edits that others find objectionable, you will not be permitted to edit at all. DMacks (talk) 21:21, 29 August 2013 (UTC)

OK I am trying to amend my ways, I thought that people were only upset about me uploading these images on specific pages. If I do something that people consider annoying please give me a chance to explain before you block me from editing because it is clearly unintended. Fuse809 (talk) 07:49, 9 September 2013 (UTC)

I must say, thanks DMacks, for giving me warning, plus thank you for having the manners of giving me some helpful feedback. Instead of just complaining and giving me no reasons! Fuse809 (talk) 10:05, 18 May 2014 (UTC)

Help me!

Hi, I'd like to know if there's anyway of getting the "Download as PDF" option for pages to actually list one's references. Additionally I'd like to know if there's any way, that any of you are aware of, of automatically creating references in the style of Wikipedia (down to the URLs given for PubMed (after PMID), PubMed Commons (after PMC) and dois (after doi:). I ask (which I'm mostly telling you so as to clarify anything confusing in how I asked my question) as I rather like Wikipedia's built-in referencing style, as it's so exhaustive, and would like to use it for my personal work. Thanks for your time, your help will be greatly appreciated!

Brenton (talk|email) (I automatically watch all pages I edit) 16:22, 31 May 2014 (UTC)

You can set up your personal wiki with the same functionality as Wikipedia; see here for the download link. Importing the {{cite doi}} and {{cite pmid}} templates isn't trivial, though. Other than that, I'm not sure what you're looking for; the only thing I could point you towards is this tool which helps create the wiki code for citations - but I don't think that's what you're looking for.
The "Download as PDF" option worked well enough for me; the PDF of the article I tested it on did include the references given in the article. Huon (talk) 19:38, 31 May 2014 (UTC)

The Pulse (WP:MED newsletter) June 2014

The first edition of The Pulse has been released. The Pulse will be a regular newsletter documenting the goings-on at WPMED, including ongoing collaborations, discussions, articles, and each edition will have a special focus. That newsletter is here.

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BMJ offering 25 free accounts to Wikipedia medical editors

Neat news: BMJ is offering 25 free, full-access accounts to their prestigious medical journal through The Wikipedia Library and Wiki Project Med Foundation (like we did with Cochrane). Please sign up this week: Wikipedia:BMJ --Cheers, Ocaasi via MediaWiki message delivery (talk) 01:14, 10 June 2014 (UTC)

Hi Brenton

Hello, although I am a Chemist I really don't know how to put together a small molecule and a protein together into a 3D model in order to view interactions. Do you know how to do this? It is very important.

Best regards,

Ivan — Preceding unsigned comment added by 79.152.31.154 (talk) 15:09, 10 June 2014 (UTC)

Jmol (http://sourceforge.net/projects/jmol/files/latest/download?source=files) is the one I usually use; but it only works if and only if, there is a 3D model found in one of the two PDB file databases (http://www.rcsb.org/pdb/home/home.do, http://www.ebi.ac.uk/pdbe/) for the macromolecule-ligand complex you're interested in. Once you've downloaded the zip file I gave you the link to, then unzip it into a new direcotry and then you can open up Jmol (which you launch as an executable java file which is found in said extracted directory) then go: File->Get PDB, and type in the PDB ID of the PDB file you've found in one of these databases. Theoretically there's another route that could work, even if there is no PDB file in these libraries, but I've never done it myself as it is beyond me and frankly it would probably take anybody at least weeks to learn how to do what you're asking for themselves, but there's a free and open-source software called AutoDock (http://autodock.scripps.edu/downloads) that could theoretically do what you're asking. Brenton (talk|email) (I automatically watch all pages I edit) 18:42, 10 June 2014 (UTC)

Medical Translation Newsletter


Wikiproject Medicine; Translation Taskforce

Medical Translation Newsletter
Issue 1, June/July 2014
by CFCF, Doc James

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This is the first of a series of newsletters for Wikiproject Medicine's Translation Task Force. Our goal is to make all the medical knowledge on Wikipedia available to the world, in the language of your choice.

note: you will not receive future editions of this newsletter unless you *sign up*; you received this version because you identify as a member of WikiProject Medicine

Spotlight - Simplified article translation


Wikiproject Medicine started translating simplified articles in February 2014. We now have 45 simplified articles ready for translation, of which the first on African trypanosomiasis or sleeping sickness has been translated into 46 out of ~100 languages. This list does not include the 33 additional articles that are available in both full and simple versions.

Our goal is to eventually translate 1,000 simplified articles. This includes:

We are looking for subject area leads to both create articles and recruit further editors. We need people with basic medical knowledge who are willing to help out. This includes to write, translate and especially integrate medical articles.

What's happening?


IEG grant
CFCF - "IEG beneficiary" and editor of this newsletter.

I've (CFCF) taken on the role of community organizer for this project, and will be working with this until December. The goals and timeline can be found here, and are focused on getting the project on a firm footing and to enable me to work near full-time over the summer, and part-time during the rest of the year. This means I will be available for questions and ideas, and you can best reach me by mail or on my talk page.

Wikimania 2014

For those going to London in a month's time (or those already nearby) there will be at least one event for all medical editors, on Thursday August 7th. See the event page, which also summarizes medicine-related presentations in the main conference. Please pass the word on to your local medical editors.

Integration progress

There has previously been some resistance against translation into certain languages with strong Wikipedia presence, such as Dutch, Polish, and Swedish.
What was found is that thre is hardly any negative opinion about the the project itself; and any such critique has focused on the ways that articles have being integrated. For an article to be usefully translated into a target-Wiki it needs to be properly Wiki-linked, carry proper citations and use the formatting of the chosen target language as well as being properly proof-read. Certain large Wikis such as the Polish and Dutch Wikis have strong traditions of medical content, with their own editorial system, own templates and different ideas about what constitutes a good medical article. For example, there are not MEDRS (Polish,German,Romanian,Persian) guidelines present on other Wikis, and some Wikis have a stronger background of country-specific content.

  • Swedish
    Translation into Swedish has been difficult in part because of the amount of free, high quality sources out there already: patient info, for professionals. The same can be said for English, but has really given us all the more reason to try and create an unbiased and free encyclopedia of medical content. We want Wikipedia to act as an alternative to commercial sources, and preferably a really good one at that.
    Through extensive collaborative work and by respecting links and Sweden specific content the last unintegrated Swedish translation went live in May.
  • Dutch
    Dutch translation carries with it special difficulties, in part due to the premises in which the Dutch Wikipedia is built upon. There is great respect for what previous editors have created, and deleting or replacing old content can be frowned upon. In spite of this there are success stories: Anafylaxie.
  • Polish
    Translation and integration into Polish also comes with its own unique set of challenges. The Polish Wikipedia has long been independent and works very hard to create high quality contentfor Polish audience. Previous translation trouble has lead to use of unique templates with unique formatting, not least among citations. Add to this that the Polish Wikipedia does not allow template redirects and a large body of work is required for each article.
    (This is somewhat alleviated by a commissioned Template bot - to be released). - List of articles for integration
  • Arabic
    The Arabic Wikipedia community has been informed of the efforts to integrate content through both the general talk-page as well as through one of the major Arabic Wikipedia facebook-groups: مجتمع ويكيبيديا العربي, something that has been heralded with great enthusiasm.
Integration guides

Integration is the next step after any translation. Despite this it is by no means trivial, and it comes with its own hardships and challenges. Previously each new integrator has needed to dive into the fray with little help from previous integrations. Therefore we are creating guides for specific Wikis that make integration simple and straightforward, with guides for specific languages, and for integrating on small Wikis.

Instructions on how to integrate an article may be found here [9]

News in short


To come
  • Medical editor census - Medical editors on different Wikis have been without proper means of communication. A preliminary list of projects is available here.
  • Proofreading drives

Further reading



Thanks for reading! To receive a monthly talk page update about new issues of the Medical Translation Newsletter, please add your name to the subscriber's list. To suggest items for the next issue, please contact the editor, CFCF (talk · contribs) at Wikipedia:Wikiproject Medicine/Translation Taskforce/Newsletter/Suggestions.
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For the newsletter from Wikiproject Medicine, see The Pulse

If you are receiving this newsletter without having signed up, it is because you have signed up as a member of the Translation Taskforce, or Wiki Project Med on meta. 22:32, 16 July 2014 (UTC)

Disambiguation link notification for July 20

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Help me, who is writing the WHO-EM cites!

Helped Hi, I have noticed that the World Health Organization's List of Essential Medicines (WHO-EM) info (like see the lead of morphine for what I mean) has been added on every page, but on every page (before I fix it, at least) there's no space between "Essential" and "Medicine" AND there's no "format=PDF" in the cite so as to warn those using their smartphones about the fact the source is a PDF. Now as the cites are very constant across all the articles I am wondering if it was a bot that did this. But whenever I view the edit history of the page I see no bot. So please, direct me to the person that's doing this so I can tell them what they're doing and ask them to make this modification to their ref. I am really uncertain as to whom is doing this, so I really think I need to ask you! Brenton (contribs · email · talk · uploads) 05:36, 22 July 2014 (UTC)

The edit was added by Jmh649. See this edit. Yes, there were quite a few done that day.--S Philbrick(Talk) 13:27, 22 July 2014 (UTC)
See this list to see other similar edits on 22 April. Please remember to AGF and discuss politely how to fix it.--S Philbrick(Talk) 13:30, 22 July 2014 (UTC)
Thank you Brenton (contribs · email · talk · uploads) 00:34, 23 July 2014 (UTC)

Help me, am I allowed to use my sandboxes to write blog posts?

Hi, I think I should explain. I have no interest in advertising my blog posts in sandboxes in articles, or on people's talk pages, neither do I have any intention on moving the content of these sandboxes into actual Wikipedia articles. So all I am using these sandboxes for is to help me with formatting, as I love the in-built formatting of Wikipedia. Now, before you say I should use MediaWiki, I have tried, on two different PCs of mine, repeatedly, to download and install this program, following the installation guides and even requesting the help of AskUbuntu but with no success. I have no intention on utilizing Wikipedia as a soapbox, I have no interest in increasing my publicity by using these sandboxes, its just explanatory documents for my friends to read. I have no interest in using photos that are not free for these sandboxes, I have no intention on breaking any rules (might be good if you were to tell me the ones you suggest I impose if your answer is OK to my request). Brenton (contribs · email · talk · uploads) 07:30, 23 July 2014 (UTC)

If what you want to do is host your blog in your user pages, I am afraid the answer is no, it would probably be nominated for deletion at WP:MFD. There relevant policy is WP:UPNOT.
But there is no need to host your own Mediawiki installation: have a look at Wikia, which also runs on the MediaWiki software, and welcomes almost any content. There may well be a suitable wiki there to host your blog, or if not you could set up your own wiki there. JohnCD (talk) 10:10, 23 July 2014 (UTC)
Thanks! Brenton (contribs · email · talk · uploads) 10:17, 23 July 2014 (UTC)

Agomelatine animation

I notice in that the GIF animation doesn't correspond to the structural formula. In the animation, the nitrogen is missing a hydrogen, and the nearby oxygen is shown as hydroxyl rather than amide. I don't have tools handy to recreate the animation myself. --Cedderstk 10:27, 27 July 2014 (UTC)

Help me, are there any users on the English Wikipedia that won't mind helping me with the MediaWiki syntax on my wiki?

I've been created my own wiki as a platform for my blogging, I've got a few questions on the creation of templates on this wiki, by copy-pasting code from the English Wikipedia and its templates. I have asked questions about this at [webmasters.stackexchange.com/questions/67496/how-do-i-get-my-wiki-to-automatically-link-dois-to-their-respective-websites WebMaster's stackexchange] and Wikia community forums, neither which have given me any results despite me asking them day(s) ago. So I thought I shouldn't put my eggs all in the one basket, hence maybe asking here might help.

Now, I'm sorry to keep asking questions, it's just I'm desperate for answers. Brenton (contribs · email · talk · uploads) 03:35, 27 July 2014 (UTC)

What you want to discuss is really unclear and I think you have used WP:help template unnecessarily. Wikipedia is not a forum to discuss instead of this you can seek for answer on yahoo answers or can Join #wikipedia-en-help connect for more help. CutestPenguin {talkcontribs} 12:14, 27 July 2014 (UTC)

Reference Errors on 16 August

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Medical Translation Newsletter Aug./Sept. 2014

Medical Translation Newsletter
Issue 2, Aug./Sept. 2014
by CFCF

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Feature – Ebola articles

Electron micrograph of an Ebola virus virion

During August we have translated Disease and it is now live in more than 60 different languages! To help us focus on African languages Rubric has donated a large number of articles in languages we haven't previously reached–so a shout out them, and Ian Henderson from Rubric who's joined us here at Wikipedia. We're very happy for our continued collaboration with both Rubric and Translators without Borders!

Just some of our over 60 translations:
New roles and guides!

At Wikimania there were so many enthusiastic people jumping at the chance to help out the Medical Translation Project, but unfortunately not all of them knew how to get started. That is why we've been spending considerable time writing and improving guides! They are finally live, and you can find them at our home-page!

New sign up page!

We're proud to announce a new sign up page at WP:MTSIGNUP! The old page was getting cluttered and didn't allow you to speficy a role. The new page should be easier to sign up to, and easier to navigate so that we can reach you when you're needed!

Style guides for translations

Translations are of both full articles and shorter articles continues. The process where short articles are chosen for translation hasn't been fully transparent. In the coming months we hope to have a first guide, so that anyone who writes medical or health articles knows how to get their articles to a standard where they can be translated! That's why we're currently working on medical good lede criteria! The idea is to have a similar peer review process to good article nominations, but only for ledes.

Some more stats
Further reading


-- CFCF 🍌 (email) 13:09, 24 September 2014 (UTC)

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3dmodel

Hi Brenton,

I'm working with an artist who would like to create a physical 3D model of the Midazolam molecule you have posted here, would it be possible to get the 3d. file from you, and if so what file format do you have it in.

my email is teecatdesign@gmail.com

Thank you — Preceding unsigned comment added by 72.10.27.178 (talk) 22:41, 8 October 2014 (UTC)

Fluvoxamine

I don't understand why the English can't call things by their regular American name like everyone else. :>)

But seriously, good catch and thanks for fixing that. Formerly 98 (talk) 14:57, 14 October 2014 (UTC)

Disambiguation link notification for October 16

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Chem molecules

Great gifs of molecules—I've just seen the one for Rosuvastatin.

Is there an easy way to stop the rotation to scrutinise it? I tried clicking/holding the cursor on it, but that doesn't do the trick.

Thanks. Tony (talk) 23:25, 19 February 2015 (UTC)

Sorry for the delay, I don't think so, unfortunately. You could save them, then use ImageMagick or another software to extract the frames as PNGs and go from there. e.g., you can run:
convert animated.gif frames%03d.png
From the command-line.Brenton (contribs · email · talk · uploads) 23:47, 23 February 2015 (UTC)