User:Mr. Ibrahem/Secukinumab

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Mr. Ibrahem/Secukinumab
Autoinjector of secukinumab by Novartis
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetIL17A
Clinical data
Trade namesCosentyx
Other namesAIN457
AHFS/Drugs.comMonograph
MedlinePlusa615011
License data
Pregnancy
category
  • AU: C
Routes of
administration
Subcutaneous
Drug classMonoclonal antibody
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only
  • EU: Rx-only[1]
  • In general: ℞ (Prescription only)
Chemical and physical data
FormulaC6584H10134N1754O2042S44
Molar mass147944.37 g·mol−1
 ☒NcheckY (what is this?)  (verify)

Secukinumab, sold under the brand name Cosentyx, is a medication used to treat psoriasis, ankylosing spondylitis, and psoriatic arthritis.[2] It is given by injection under the skin.[3]

Common side effects include a runny nose, diarrhea, cold sores, and hives.[3] Other side effects may include anaphylaxis and infection.[3] Use during pregnancy or breastfeeding is not recommended.[4] It is a monoclonal antibody that binds to and inhibits interleukin (IL)-17A.[3]

Secukinumab was approved for medical use in the United States and Europe in 2015.[3][2] In the United Kingdom 150 mg costs the NHS about £600 as of 2021.[4] This amount in the United States costs about 6,200 USD.[5]

References[edit]

  1. ^ "Cosentyx EPAR". European Medicines Agency (EMA). Archived from the original on 22 August 2020. Retrieved 23 September 2020.
  2. ^ a b c "Cosentyx". Archived from the original on 22 August 2020. Retrieved 11 October 2021.
  3. ^ a b c d e f "Secukinumab Monograph for Professionals". Drugs.com. Archived from the original on 4 March 2021. Retrieved 11 October 2021.
  4. ^ a b BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 1162. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)
  5. ^ "Cosentyx Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 22 June 2021. Retrieved 11 October 2021.