User:Mr. Ibrahem/Indacaterol

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Mr. Ibrahem/Indacaterol
Clinical data
Trade namesArcapta, Onbrez, others
Other namesIndacaterol maleate
AHFS/Drugs.comMonograph
License data
Pregnancy
category
  • AU: B3
Routes of
administration
Inhalation
Drug classLong-acting beta-adrenoceptor agonist (LABA)[1]
Legal status
Legal status
Identifiers
  • 5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one
Chemical and physical data
FormulaC24H28N2O3
Molar mass392.499 g·mol−1
3D model (JSmol)
  • O=C4/C=C\c1c(c(O)ccc1[C@@H](O)CNC3Cc2cc(c(cc2C3)CC)CC)N4
  • InChI=1S/C24H28N2O3/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29)/t22-/m0/s1 checkY
  • Key:QZZUEBNBZAPZLX-QFIPXVFZSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Indacaterol, sold under the brand name Onbrez among others, is a medication used to treat chronic obstructive pulmonary disease (COPD).[1] Is is used by dry powder inhaler once per day.[1]

Common side effects include upper respiratory tract infection, chest pain, and cough.[6] In those with asthma it may increase the risk of death.[1] It is a long-acting beta-adrenoceptor agonist (LABA).[1]

Indacaterol was approved for medical use in Europe in 2009 and the United States in 2011.[6][1] In the United Kingdom it costs the NHS about £32 a month as of 2021.[7] In the United States this amount costs about 260 USD.[8]

References[edit]

  1. ^ a b c d e f g h "Indacaterol Monograph for Professionals". Drugs.com. Archived from the original on 22 January 2021. Retrieved 26 November 2021.
  2. ^ "Arcapta Neohaler (indacaterol) inhalation powder Initial U.S. Approval: 2011". DailyMed. 1 April 2020. Archived from the original on 15 June 2021. Retrieved 14 June 2021.
  3. ^ "Onbrez Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.
  4. ^ "Oslif Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.
  5. ^ "Hirobriz Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.
  6. ^ a b c d "Onbrez Breezhaler". Archived from the original on 28 January 2021. Retrieved 26 November 2021.
  7. ^ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 267. ISBN 978-0857114105.
  8. ^ "Indacaterol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 26 November 2021.