RLF (gene)

RLF
Identifiers
Aliases	RLF, ZN-15L, ZNF292L, rearranged L-myc fusion, RLF zinc finger
External IDs	OMIM: 180610 MGI: 1924705 HomoloGene: 8243 GeneCards: RLF
Gene location (Human) Chr. Chromosome 1 (human) Band 1p34.2 Start 40,161,387 bp End 40,240,921 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 D2.2 Start 121,002,570 bp End 121,072,281 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte Achilles tendon sperm endothelial cell embryo ganglionic eminence middle temporal gyrus Brodmann area 23 amniotic fluid bone marrow Top expressed in saccule otic placode hand maxillary prominence dermis left lung lobe belly cord foot medial ganglionic eminence ciliary body More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding zinc ion binding protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process positive regulation of transcription, DNA-templated regulation of transcription, DNA-templated DNA integration chromosome organization transcription, DNA-templated positive regulation of transcription by RNA polymerase II regulation of DNA methylation histone H3-K4 monomethylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6018 109263 Ensembl ENSG00000117000 ENSMUSG00000049878 UniProt Q13129 n/a RefSeq (mRNA) NM_012421 NM_001081013 NM_001346660 RefSeq (protein) NP_036553 n/a Location (UCSC) Chr 1: 40.16 – 40.24 Mb Chr 4: 121 – 121.07 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein Rlf is a protein that in humans is encoded by the RLF gene.

Further reading

• Olsen JV; Blagoev B; Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Gregory SG; Barlow KF; McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j.1471-4159.2006.03836.x. PMC 2239266. PMID 16696853.
• Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Colland F; Jacq X; Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Lanigan TM; Liu A; Huang YZ; et al. (2003). "Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf". FASEB J. 17 (14): 2048–60. doi:10.1096/fj.02-1096com. hdl:2027.42/154294. PMID 14597674. S2CID 22523818.
• Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Shao H, Kadono-Okuda K, Finlin BS, Andres DA (1999). "Biochemical characterization of the Ras-related GTPases Rit and Rin". Arch. Biochem. Biophys. 371 (2): 207–19. doi:10.1006/abbi.1999.1448. PMID 10545207.
• Mäkelä TP; Hellsten E; Vesa J; et al. (1996). "The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein". Oncogene. 11 (12): 2699–704. PMID 8545128.