File talk:Signal transduction pathways.png
This Signal Transduction pathway is too old. The "Vascular Endothelial Growth Factor" VEGF is missing.
TNF is misplaced; IkB function is the opposite[edit]
- TNF-alpha doesn't bind to Fas Receptor, but rather to its own cytokine receptor (in fact TNF is the paradigmatic example capable to activate apoptosis by a different pathway other than the intrinsic [Cytochrome C] or the extrinsic [FasL] pathway).
- IkB acts as an NF-kB inhibitor instead of an activator, thus its name.
80.174.254.211 (talk) 08:13, 30 December 2010 (UTC)