File talk:Signal transduction pathways.png

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This Signal Transduction pathway is too old. The "Vascular Endothelial Growth Factor" VEGF is missing.

TNF is misplaced; IkB function is the opposite[edit]

  1. TNF-alpha doesn't bind to Fas Receptor, but rather to its own cytokine receptor (in fact TNF is the paradigmatic example capable to activate apoptosis by a different pathway other than the intrinsic [Cytochrome C] or the extrinsic [FasL] pathway).
  2. IkB acts as an NF-kB inhibitor instead of an activator, thus its name.

80.174.254.211 (talk) 08:13, 30 December 2010 (UTC)[reply]