File:Patch Clamp Chip.svg
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Summary
| Description |
English: A patch clamp chip designed to record electrical currents in single cells. These are typically used in ion channel drug screening studies. One example is testing depression medications for their effect on ion channels in neurons. Typically the ion channels are genetically grafted into a heart or kidney cell so the neuron ion channel can be used with the patch chip. This patch chip has an inner recording chamber filled with intracellular fluid and an outer chamber filled with extracellular fluid. A whole cell patch clamp recording can be made after the cell forms a "giga seal" with the patch chip which directs the cell currents into the intracellular chamber where the amplifier can measure the ionic currents. |
| Date | |
| Source | Own work |
| Author | Gregory Holst |
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Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled GNU Free Documentation License. |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 23:16, 12 November 2012 | | 1,877 × 793 (68 KB) | Gregory Holst | Trying to resubmit, it's not working... |
| 23:14, 12 November 2012 |  | 1,877 × 793 (68 KB) | Gregory Holst | Adding whitespace and perimeter box. | |
| 23:12, 12 November 2012 |  | 1,877 × 798 (68 KB) | Gregory Holst | Adding whitespace on the right. It didn't work the last time. | |
| 23:10, 12 November 2012 |  | 1,877 × 798 (68 KB) | Gregory Holst | Added whitespace on the right of the image. | |
| 17:52, 12 November 2012 |  | 1,863 × 798 (68 KB) | Gregory Holst | Minor visible lines dividing the image. Slight corrections | |
| 17:38, 12 November 2012 |  | 1,863 × 798 (68 KB) | Gregory Holst | {{Information |Description ={{en|1=A patch clamp chip designed to record electrical currents in single cells. These are typically used in ion channel drug screening studies. One example is testing depression medications for their effect on ion cha... |
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