File:PPARalpha transcriptome.png

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Summary

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English: Detailed overview map of metabolic genes upregulated by PPARα in mouse liver. The map is based on the published literature combined with transcriptomics analysis of liver of WT and PPARα-/- mice. Colors indicate whether expression of a gene is governed by PPARα during fasting (In green: significantly decreased expression in fasted PPARα-/- mice compared to fasted PPARα+/+ mice), and/or by synthetic PPARα agonists (In blue: significantly increased expression in WT mice treated with Wy14643 or fenofibrate compared to vehicle-treated WT mice). Genes shown in red are upregulated by PPARα during fasting and are upregulated by Wy14643/fenofibrate.
Date
Source Template:Based on published literature
Author Sander Kersten

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26 April 2013

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Date/TimeThumbnailDimensionsUserComment
current07:55, 18 October 2023Thumbnail for version as of 07:55, 18 October 20233,466 × 2,454 (1.41 MB)Sander kerstenUpdate 2023
21:06, 7 October 2015Thumbnail for version as of 21:06, 7 October 20153,445 × 2,410 (1.8 MB)Sander kerstenMinor update
09:11, 29 May 2014Thumbnail for version as of 09:11, 29 May 20143,445 × 2,410 (1.76 MB)Sander kerstenupdated, a few new genes added
21:20, 6 February 2014Thumbnail for version as of 21:20, 6 February 20143,445 × 2,410 (1.74 MB)Sander kerstenupdate
15:46, 7 August 2013Thumbnail for version as of 15:46, 7 August 20133,445 × 2,410 (1.7 MB)Sander kerstenReverted to version as of 15:45, 7 August 2013
15:46, 7 August 2013Thumbnail for version as of 15:46, 7 August 20133,445 × 2,410 (1.7 MB)Sander kerstenReverted to version as of 16:01, 6 August 2013
15:45, 7 August 2013Thumbnail for version as of 15:45, 7 August 20133,445 × 2,410 (1.7 MB)Sander kerstenReverted to version as of 16:01, 6 August 2013
13:50, 7 August 2013Thumbnail for version as of 13:50, 7 August 20133,445 × 2,410 (1.7 MB)Sander kerstensmall correction
16:01, 6 August 2013Thumbnail for version as of 16:01, 6 August 20133,445 × 2,410 (1.7 MB)Sander kerstensmall correction
15:01, 6 August 2013Thumbnail for version as of 15:01, 6 August 20133,445 × 2,410 (1.7 MB)Sander kerstensmall corrections
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