Summary

DescriptionMiRNA-biogenesis.jpg	English: Overview of microRNA processing in animals, from transcription to the formation of the effector complex. There are two pathways, one for microRNAs from independent genes and one for intronic microRNAs. Enzymes in the picture: Drosha, Pasha (pri-miRNA → pre-miRNA) Spliceosome (pre-mRNA → intron lariat) Debranching enzyme (intron lariat → RNA that can fold into pre-miRNA) RAN-GTP, Exportin-5 (export from nucleus) Dicer (pre-miRNA → miRNA) Abbrevations: pri-miRNA = primary microRNA transcript pre-mRNA = precursor messenger RNA pre-miRNA = precursor microRNA miRNA = microRNA miRNA* = antisense microRNA miRNP = microRNA ribonucleoprotein עברית: תהליכים בסינתזה של MicroRNA
Date	13 April 2009
Source	Own work (Original text: I created this work entirely by myself.) References: Esquela-Kerscher A, Slack FJ (2006) Oncomirs — microRNAs with a role in cancer. Nat Rev Cancer 6: 259–69. PubMed Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC (2007) The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130: 89–100. PubMed
Author	Narayanese (talk)
Other versions	This biology image could be re-created using vector graphics as an SVG file. This has several advantages; see Commons:Media for cleanup for more information. If an SVG form of this image is available, please upload it and afterwards replace this template with {{vector version available|new image name}}. It is recommended to name the SVG file “MiRNA-biogenesis.svg”—then the template Vector version available (or Vva) does not need the new image name parameter. This biology image was uploaded in the JPEG format even though it consists of non-photographic data. This information could be stored more efficiently or accurately in the PNG or SVG format. If possible, please upload a PNG or SVG version of this image without compression artifacts, derived from a non-JPEG source (or with existing artifacts removed). After doing so, please tag the JPEG version with {{Superseded|NewImage.ext}} and remove this tag. This tag should not be applied to photographs or scans. If this image is a diagram or other image suitable for vectorisation, please tag this image with {{Convert to SVG}} instead of {{BadJPEG}}. If not suitable for vectorisation, use {{Convert to PNG}}. For more information, see {{BadJPEG}}.

Licensing

Narayanese at English Wikipedia, the copyright holder of this work, hereby publishes it under the following license:

This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.

Attribution: Narayanese at English Wikipedia

You are free:

• to share – to copy, distribute and transmit the work
• to remix – to adapt the work

Under the following conditions:

• attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
• share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.

https://creativecommons.org/licenses/by-sa/3.0CC BY-SA 3.0 Creative Commons Attribution-Share Alike 3.0 truetrue

Original upload log

• 2009-04-13 18:00 Narayanese 1520×1610× (356456 bytes) removed PolII from picture
• 2009-04-13 17:33 Narayanese 1520×1610× (379131 bytes) {{Information |Description = microRNA biosynthesis |Source = I created this work entirely by myself. |Date = 13 April 2009 |Author = ~~~ |other_versions = }}

• 2009-12-03 08:34 Adiel lo 1520×1610× (356456 bytes) ==תקציר== {{מידע| |תיאור=תהליכים בסינתזה של [[MicroRNA]] |מקור=ויקיפדיה אנגלית [http://en.wikipedia.org/wiki/File:MiRNA-biogenesis.jpg[ |תאריך יצירה= |יוצר=http://en.wikipedia.org/wiki/User:Nar