File:Lipid bilayer expansion hypothesis of anesthetic effect.png

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English: bulky and hydrophobic anesthetic molecules accumulate inside the neuronal cell membrane causing its distortion and expansion (thickening) due to volume displacement. Membrane thickening reversibly alters function of membrane ion channels thus providing anesthetic effect. Actual chemical structure of the anesthetic agent per se was not important, but its molecular volume plays the major role: the more space within membrane is occupied by anesthetic - the greater is the anesthetic effect.
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Author Akuznetsova
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20 April 2009

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current20:53, 21 April 2009Thumbnail for version as of 20:53, 21 April 20091,150 × 626 (44 KB)Akuznetsova{{Information |Description={{en|1=bulky and hydrophobic anesthetic molecules accumulate inside the neuronal cell membrane causing its distortion and expansion (thickening) due to volume displacement. Membrane thickening reversibly alters function of membr
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