File:Interpretation of the Cutoff effect in the frame of protein hypothesis of anesthetic mechanism.png

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English: The Meyer-Overton rule predicts the constant increase of anesthetic potency in the raw of n-alkanols with the increase of n-alkanol chain length. However, n-alkanols with chain length above certain “cutoff” length surprisingly lack anesthetic effect because their hydrocarbon chain volume starts to exceed volume of the putative binding site on the protein.
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Author Akuznetsova
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19 April 2009

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current21:03, 21 April 2009Thumbnail for version as of 21:03, 21 April 20091,374 × 639 (69 KB)Akuznetsova{{Information |Description={{en|1=The Meyer-Overton rule predicts the constant increase of anesthetic potency in the raw of n-alkanols with the increase of n-alkanol chain length. However, n-alkanols with chain length above certain “cutoff” length sur
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