File:CAPON Binds Nitric Oxide Synthase, Regulating NMDA Receptor–Mediated Glutamate Neurotransmission.png

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English: Binding of CAPON results in a reduction of NMDA receptor/nitric oxide synthase (NOS) complexes, leading to decreased NMDA receptor–gated calcium influx and a catalytically inactive nitric oxide synthase. Overexpression of either the full-length or the novel shortened CAPON isoform as reported by Brzustowicz and colleagues is, therefore, predicted to lead to impaired NMDA receptor–mediated glutamate neurotransmission.
Date
Source Does the CAPON Gene Confer Susceptibility to Schizophrenia?
Author Bang Wong
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Date/TimeThumbnailDimensionsUserComment
current23:35, 2 January 2022Thumbnail for version as of 23:35, 2 January 20221,370 × 956 (428 KB)Jul059Lossless file size reduction
11:34, 25 April 2009Thumbnail for version as of 11:34, 25 April 20091,370 × 956 (493 KB)CopperKettle{{Information |Description={{en|1=Binding of CAPON results in a reduction of NMDA receptor/nitric oxide synthase (NOS) complexes, leading to decreased NMDA receptor–gated calcium influx and a catalytically inactive nitric oxide synthase. Overexpression
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