RHPN1

RHPN1
Identifiers
Aliases	RHPN1, ODF5, RHOPHILIN, RHPN, rhophilin, Rho GTPase binding protein 1, rhophilin Rho GTPase binding protein 1
External IDs	OMIM: 601031 MGI: 1098783 HomoloGene: 7346 GeneCards: RHPN1
Gene location (Human) Chr. Chromosome 8 (human) Band 8q24.3 Start 143,368,876 bp End 143,384,221 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 D3 Start 75,576,129 bp End 75,587,334 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland anterior pituitary right uterine tube nucleus accumbens Brodmann area 9 amygdala cingulate gyrus caudate nucleus hypothalamus Top expressed in saccule spermatocyte spermatid otic placode proximal tubule renal corpuscle superior frontal gyrus yolk sac renal calyx seminiferous tubule More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytosol Biological process signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 114822 14787 Ensembl ENSG00000158106 ENSMUSG00000022580 UniProt Q8TCX5 Q61085 RefSeq (mRNA) NM_052924 NM_001163465 NM_008164 RefSeq (protein) NP_443156 NP_001156937 NP_032190 Location (UCSC) Chr 8: 143.37 – 143.38 Mb Chr 15: 75.58 – 75.59 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Rhophilin-1 is a protein that in humans is encoded by the RHPN1 gene.

Further reading

• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Jaffe AB, Aspenström P, Hall A (2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Mol. Cell. Biol. 24 (4): 1736–46. doi:10.1128/MCB.24.4.1736-1746.2004. PMC 344169. PMID 14749388.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Peck JW, Oberst M, Bouker KB, et al. (2003). "The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization". J. Biol. Chem. 277 (46): 43924–32. doi:10.1074/jbc.M203569200. PMID 12221077.
• Fujita A, Nakamura K, Kato T, et al. (2000). "Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella". J. Cell Sci. 113 (1): 103–12. doi:10.1242/jcs.113.1.103. hdl:2433/181273. PMID 10591629.