File:Intramolecular cyclization of cis-rotamer.svg

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English: Here is shown the conversion of the trans-rotamer to cis-rotamer, which undergoes intramolecular cyclization, losing enzyme-inhibiting activity. This problem occurred during the development of DPP-4 inhibitors vildagliptin and saxagliptin. Created with ChemDoodle 7.0.2 and Adobe Illustrator CC 2015.
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Source Own work
Author Vaccinationist
 
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Public domain This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship.

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10 July 2015

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Date/TimeThumbnailDimensionsUserComment
current11:51, 10 November 2016Thumbnail for version as of 11:51, 10 November 2016512 × 437 (28 KB)Vaccinationistfonts
12:32, 10 July 2015Thumbnail for version as of 12:32, 10 July 2015512 × 436 (39 KB)Vaccinationistchanged some parts to emphasize cyclization
12:21, 10 July 2015Thumbnail for version as of 12:21, 10 July 2015512 × 436 (39 KB)VaccinationistUser created page with UploadWizard
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