MAATS1

CFAP91
Identifiers
Aliases	CFAP91, AAT1, AAT1alpha, C3orf15, CaM-IP2, SPATA26, MYCBP associated and testis expressed 1, MAATS1, cilia and flagella associated protein 91, SPGF51
External IDs	OMIM: 609910 MGI: 2443598 HomoloGene: 33470 GeneCards: CFAP91
Gene location (Human)
Chr.	Chromosome 3 (human)
End	119,767,102 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	38,162,505 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; pituitary gland; ; anterior pituitary; ; sperm; ; body of pancreas; ; caput epididymis; ; pancreatic epithelial cell; ; pancreatic ductal cell; ; spleen;
	Top expressed in
	utricle; ; spermatid; ; seminiferous tubule; ; spermatocyte; ; olfactory epithelium; ; right lung lobe; ; morula; ; habenula; ; paraventricular nucleus of hypothalamus; ; median eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; mitochondrion; radial spoke stalk; axoneme; motile cilium; cytoskeleton; cell projection;
Biological process	cilium movement;
	Sources:Amigo / QuickGO
Orthologs
	89876
	320214
	ENSG00000183833
	ENSMUSG00000022805
	Q7Z4T9
	Q8BRC6
	NM_033364; NM_001320316; NM_001320317; NM_001320318
	NM_001081025; NM_177104
	NP_001307245; NP_001307246; NP_001307247; NP_203528
	NP_001074494
	Wikidata
View/Edit Human	View/Edit Mouse

AMY-1-associating protein expressed in testis 1 is a protein that in humans is encoded by the MAATS1 (formerly known as C3orf15) gene.^[5]^[6]^[7]

Interactions[edit]

C3orf15 has been shown to interact with MYCBP^[5] and AKAP1.^[5]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183833 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022805 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b ^c Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". J Biol Chem. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.
^ Hayes VM, Gardiner-Garden M (Oct 2003). "Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease?". J Infect Dis. 188 (8): 1205–8. doi:10.1086/378641. PMID 14551891.
^ "Entrez Gene: C3orf15 chromosome 3 open reading frame 15".

External links[edit]

Human MAATS1 genome location and MAATS1 gene details page in the UCSC Genome Browser.

Further reading[edit]

Matsuda E, Ishizaki R, Taira T, et al. (2005). "Structure and characterization of AAT-1 isoforms" (PDF). Biol. Pharm. Bull. 28 (5): 898–901. doi:10.1248/bpb.28.898. PMID 15863901.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Talmud PJ, Martin S, Steiner G, et al. (2004). "Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene". Arterioscler. Thromb. Vasc. Biol. 23 (4): 644–9. doi:10.1161/01.ATV.0000065196.61663.8D. PMID 12692006.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mashiba S, Wada Y, Takeya M, et al. (2001). "In vivo complex formation of oxidized alpha(1)-antitrypsin and LDL". Arterioscler. Thromb. Vasc. Biol. 21 (11): 1801–8. doi:10.1161/hq1101.098232. PMID 11701469.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183833 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022805 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12223483-5] Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". J Biol Chem. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.

[pmid14551891-6] Hayes VM, Gardiner-Garden M (Oct 2003). "Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease?". J Infect Dis. 188 (8): 1205–8. doi:10.1086/378641. PMID 14551891.

[entrez-7] "Entrez Gene: C3orf15 chromosome 3 open reading frame 15".

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